Karen Jerome-Zapadka

Current: Founder and Medical Director, Trajectory Health Partners-A Center for Metabolic, Liver and Obesity Medicine
Past: Past President of the Board and Current Member, Valley Gastroenterology Associates, 2000-present Founder and Past Medical Director, VGA Center for Obesity Medicine Founder and Co-chair, Metabolic Task Force of HVHS; Past President of Medical Staff; Past Board of Directors Member, Heritage Valley Health System (HVHS) Chairman of the Board-Elect, Liver Education Advocates Past Co-chair, Fatty Liver Coalition, Community Liver Alliance Founding Member, The Society for Metabolic Health Practitioners

Dr. Jerome-Zapadka is a leading expert in metabolic health and gastroenterology, specializing in the root causes and reversal of chronic metabolic conditions such as fatty liver disease, insulin resistance, and type 2 diabetes. Her work focuses on therapeutic carbohydrate reduction, ketogenic metabolic therapy, and sustainable lifestyle interventions to restore metabolic function and improve long-term health outcomes. With a patient-centered approach grounded in the latest clinical research, she is committed to transforming how metabolic dysfunction is understood and treated. Dr. Jerome-Zapadka is recognized for her leadership in applying nutrition and lifestyle-based strategies to prevent and reverse disease through individualized care.

Awards

  • University of Pittsburgh School of Medicine – Honors graduate
  • AOA Alpha Omega Alpha –  Medical Honorary Society
  • Pittsburgh Magazine Top Doctors 2021-2024

Top Publications

  • Jerome-Zapadka KM, et al   American Journal of Gastroenterology 1994 PMID: 8122657
  • Recurrent upper esophageal webs in association with heterotopic gastric mucosa: case report and literature review.
  • Teicholz N, et al   Nutrients  2025, 17(6), 1047  Myths and Facts Regarding Low-Carbohydrate Diets nu1706104710.3390 https://doi.org2025 

Years of Clinical Experience & Estimated Number of Patients Treated

5 years in residency and fellowship, 32 years in clinical practice, thousands of patients