Lori Calabrese

Dr. Lori Calabrese trained at The Johns Hopkins University School of Medicine and Harvard Medical School and has held faculty positions at both Harvard and Yale. She is one of only a handful of physicians worldwide recognized as a Nutrition Network Certified Medical Practitioner.

With more than three decades of clinical experience and over 25,000 patients treated, Dr. Calabrese has pioneered the use of whole-foods ketogenic metabolic therapy in psychiatry and medicine. She published the first clinical cases demonstrating complete remission of severe, treatment-resistant anorexia nervosa, major depression, complex anxiety disorders, and obsessive–compulsive disorder, along with remission of ulcerative colitis—contributions that helped establish metabolic therapy as a transformative intervention in psychiatry.

She has authored seventeen peer-reviewed publications, and is the author of Toxic Roots: The Rewiring of Our Generation – and the Science of Doing a 180 coming out in Fall, 2025. She is widely recognized for integrating neuroscience, nutrition, and metabolic medicine into innovative care models that emphasize recovery and sustained remission.

Awards & Honors

• International Rotary Foundation Scholar
• Dean’s Fund Scholar, The Johns Hopkins University School of Medicine
• NIMH Outstanding Resident Award
• Thomas P. Hackett Award, Massachusetts General Hospital and Harvard Medical School
• Academy of Psychosomatic Medicine Best Poster
• Psychiatrist of the Year, Eastern Connecticut Health Network
• Multiple Top Doctors honors spanning two decades
• Summa Cum Laude, Nutrition Network Medical Certification Pathway

Number of publications

17 peer-reviewed publications, author of the book Toxic Roots: The Rewiring of Our Generation—and the Science of Doing a 180

Years of Clinical Experience and Estimated Number of Patients Treated

32 years and more than 25,000 patients