The Evidence Connecting Nutrition, Metabolic Health and Major Chronic Conditions

Chronic diseases affect millions of people and place a significant burden on the U.S. healthcare system. Three in four U.S. adults have at least one chronic illness. Diabetes alone accounts for an estimated $413 billion in U.S. economic costs per year, while cardiovascular disease and obesity combined account for trillions more annually. 

Dietary interventions have the potential to dramatically reduce the burden of chronic disease. Rigorous research can help establish which approaches work best and define their role in clinical care and health policy.

Our evidence briefs examine the connections between nutrition, metabolic health and major chronic diseases, including what the current research shows about low-carbohydrate and ketogenic therapies. 

Developed with input from leading clinicians and researchers, the briefs offer accessible summaries for leaders in policy, public health, research, and clinical care from the federal to the community level. Each brief summarizes evidence on the impact of the condition, its relationship to metabolic health, the role of dietary interventions in prevention or treatment, as well as priorities for future research.